Human melanoma stained with anti-HMB-45 antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of melanoma cells.

Melanosome

Dermatopathology

HMB-45 Mouse Monoclonal

By immunohistochemistry, HMB-45 specifically recognizes a protein in melanocytes and melanomas. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Melanoma

Visualization:Cytoplasmic

Isotype:IgG1 /κ

Immunogen:Extract of pigmented melanoma metastases from lymph nodes

Ordering Information

USA International

Package Inserts

IFU-Melanosome HMB-45

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

Accept Reject

SDS