Human melanoma stained with anti-Melan-A antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of melanoma cells.
MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. MART-1 is present in melanosomes and endoplasmic reticulum. Clone 103 does not cross-react with MAGE-1 or tyrosinase protein. Clone 103 labels melanomas and other tumors showing melanocytic differentiation. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Specifications
Species Reactivity:Humans; others not tested
Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Supplied As:Buffer with protein carrier and preservative
Storage:Store at 2ºC to 8ºC
Control:Skin or melanoma
Visualization:Cytoplasmic
Isotype:IgG1 /κ
Immunogen:Recombinant MART-1 protein
Ordering Information
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