Human melanoma stained with anti-Melan-A antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of melanoma cells.

Melan-A (MART-1)

Dermatopathology

A103 Mouse Monoclonal

Zeta’s mouse monoclonal antibodies recognize Melan-A (MART-1). MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Melan-A/MART-1 is present in melanosomes and endoplasmic reticulum. Melan-A (MART-1) Clone 103 does not cross-react with MAGE-1 or tyrosinase protein. Melan-A (MART-1) Clone 103 labels melanomas and other tumors showing melanocytic differentiation. The antibody to Melan-A (MART-1) does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Skin or melanoma

Visualization:Cytoplasmic

Isotype:IgG1 /κ

Immunogen:Recombinant MART-1 protein

Ordering Information

USA International

Package Inserts

IFU-Melan-A (MART-1) A103 - IVDL

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

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SDS