Preferred Clone

Formalin-fixed, paraffin-embedded human adult granulosa cell tumor stained with anti-FOXL2 antibody using peroxidase-conjugate and DAB chromogen. Note nuclear staining of tumor cells

FOXL2

Neuropathology/Endocrine

ZR399 Rabbit Monoclonal

FOXL2 is a critical factor essential for ovary differentiation and maintenance and repression of the genetic program for somatic testis determination. It prevents trans-differentiation of the ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9. FOXL2 is mainly expressed in the ovary, parathyroid gland, and sex cord-stromal tumors. FOXL2 is generally used to diagnose sex cord-stromal tumors with inhibin, calretinin, and SF-1.

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Ovarian follicular and stromal cells

Visualization:Nucleus

Isotype:IgG

Immunogen:Recombinant full-length human FOXL2 protein

Ordering Information

USA International

Package Inserts

IFU-FOXL2 ZR399 - IVD 0

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

Accept Reject

IFU-FOXL2 ZR399 - RUO 0

Regulatory Notice

Accept Reject

SDS