Zeta CD43 Antibody. Zeta’s monoclonal mouse antibody recognizes CD43 (leukosialin, sialophorin, or leukocyte sialoglycoprotein), a cell surface glycoprotein which is expressed on all thymocytes and T-cells. CD43 is involved in activation of T cells, B cells, NK cells, and monocytes.
CD43 is a pan T cell marker important in T cell and neutrophil adhesion to endothelium. CD43 serves as a ligand for E-selectin on T cells and may regulate T cell trafficking and has both antiadhesive and proadhesive roles in neutrophil rolling. CD43 is used to diagnose myeloid (granulocytic) sarcoma, to classify subtypes of T cell lymphomas and low grade B cell lymphomas, and to differentiate pulmonary MALT lymphoma (CD20+ CD43+) from lymphoid hyperplasia (CD43 negative).
Zeta Corporation is a leader in recombinant monoclonal IVD antibodies for immunohistochemistry (IHC) offering 400+ tumor and tissue specific relevant products developed by a pathologist for pathologists. Visit Precision Recombinant Antibodies – IVD Antibodies – About Zeta Corporation (zeta-corp.com) to learn more about Zeta Corporation.