CD5

    Hematopathology
    ZM61 Monospecific Mouse Monoclonal

    Zeta CD5 Antibody.  Zeta’s recombinant mouse antibody recognizes CD5, which is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, CD5 is expressed in T cell areas.  CD5 is a 67kDa transmembrane protein.  CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. The CD5 antibody detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23.  The CD5 antibody is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, the antibody to CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). The CD5 antibody does not react with granulocytes or monocytes.

    Zeta Corporation is a leader in recombinant monoclonal IVD antibodies for immunohistochemistry (IHC) offering 400+ tumor and tissue specific relevant products developed by a pathologist for pathologists.  Visit Precision Recombinant Antibodies – IVD Antibodies – About Zeta Corporation (zeta-corp.com) to learn more about Zeta Corporation.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Tonsil
    Visualization:Membrane
    Isotype:IgG2b /κ
    Immunogen:Recombinant human CD5 protein fragment (around aa 269-366) (exact sequence is proprietary)
    Ordering Information
    Classification IVD
    Catalogue Number Z2371ML
    Classification IVD
    Catalogue Number Z2371ML
    Package Inserts
    IFU-CD5 ZM61 - IVDL
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS