Zeta Synaptophysin Antibody. Zeta’s rabbit recombinant antibody recognizes Synaptophysin, an N-glycosylated integral membrane protein found in neurons and endocrine cells. Synaptophysin contains four transmembrane domains and may function as a gap junction-like channel. Zeta’s recombinant Synaptophysin antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which correlates with the distribution of the antigen within neurosecretory vesicles. Synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.
Synaptophysin is a protein that can be demonstrated in a range of neural and neuroendocrine tissues using IHC. Synaptophysin is a specific marker for these tissues and can be used to identify tumors arising form them. Pathologists often perform IHC to help identify synaptophysin-producing cells in tissue samples.
Zeta Corporation is a leader in recombinant monoclonal IVD antibodies for immunohistochemistry (IHC) offering 400+ tumor and tissue specific relevant products developed by a pathologist for pathologists. Visit Precision Recombinant Antibodies – IVD Antibodies – About Zeta Corporation (zeta-corp.com) to learn more about Zeta Corporation.