ZM57 Monospecific Mouse Monoclonal

    SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. It is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct3/4 expression.SOX-2 is expressed in teratoma and CNS astrocytic tumors.

    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Normal brain tissue and astrocytoma
    Isotype:IgG2b /κ
    Immunogen:Recombinant human SOX2 protein fragment (around aa176-305)
    Ordering Information
    Classification IVD
    Catalogue Number Z2367ML
    Classification IVD
    Catalogue Number Z2367ML
    Package Inserts
    IFU-SOX-2 ZM57
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.