Human brain stained with anti-GFAP antibody using peroxidase-conjugate and DAB chromogen. Note positive staining of astrocytic processes.
Glial Fibrillary Acidic Protein (GFAP) is specific to astrocytes (i.e., glial cells) and ependymal cells of the central nervous system. MAb to GFAP is useful in differentiating primary gliomas from metastatic lesions in the brain and for documenting astrocytic differentiation in tumors outside the CNS. GFAP stains astrocytes, glial cells, ependymal cells, and their corresponding tumors. Many types of neural tumors such as neuroblastomas, Schwannomas, as well as extra-CNS tumors are not labeled. GA-5 is very sensitive in detecting GFAP in routine formalin-fixed, paraffin-embedded tissues.
Specifications
Species Reactivity:Humans; others not tested
Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Supplied As:Buffer with protein carrier and preservative
Storage:Store at 2ºC to 8ºC
Control:Brain or astrocytoma
Visualization:Cytoplasmic
Isotype:IgG1 /κ
Immunogen:Native GFAP purified from pig spinal cord
Ordering Information
Package Inserts
SDS