Preferred Clone

Human seminoma stained with anti-OCT-4 antibody using peroxidase-conjugate and DAB chromogen. Note the nuclear staining of tumor cells.

OCT-4

Urinary Pathology

ZR364 Rabbit Monoclonal

OCT4 is a member of the POU family of transcription factors, is involved in regulating pluripotency during normal development, and is detectable in embryonic stem and germ cells. OCT4 is a crucial regulator of self-renewal in embryonic stem cells; its expression is potentially correlated with tumorigenesis and can affect tumor recurrence or resistance to therapies. OCT4 is expressed in undifferentiated pluripotent cells, germ cells in the ovary, and testes. OCT4 Ab is useful in the identification of primary as well as metastatic germ cell tumors.

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Seminoma

Visualization:Nuclear

Isotype:IgG

Immunogen:Recombinant fragment of human OCT-4/POU5F1 protein (exact sequence is proprietary)

Ordering Information

USA International

Package Inserts

IFU-OCT-4 ZR364

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

Accept Reject

SDS