Human testicular seminoma stained with anti-D2-40 antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of tumor cells and endothelial cells of lymphatic channels.

Podoplanin

Gynecological Pathology

D2-40 Mouse Monoclonal

Monoclonal antibody, D2-40 reacts with a O-linked sialoglycoprotein (MW 40K) found on lymphatic endothelium, fetal testis and on the surface of testicular germ cell tumors. In recent studies (see datasheet) clone D2-40 have shown staining in lymphatic channel endothelium but not in the adjacent capillary. In the same study, Clone D2-40 has shown staining in endothelium of lymphangiomas whereas hemangiomas, glomus tumors, angiolipomas, pyogenic granulomas, vascular malformations did not show any staining.

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Germ cell tumor

Visualization:Cytoplasmic

Isotype:IgG1 /κ

Immunogen:M2A

Ordering Information

USA International

Package Inserts

IFU-Podoplanin D2-40

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

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SDS