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    ZM24 Monospecific Mouse Monoclonal

    Recognizes a protein of about 50kDa, which is identified as gamma-enolase. Three isoenzymes of enolases are identified, alpha, beta and gamma. Alpha-isoform is expressed in most tissues, whereas beta-form is expressed predominantly in muscle tissue whereas gamma-enolase is found only in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE-gamma is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins, such as pheochromocytomas. It be usually employed in combination with other markers such as synaptophysin, Chromogranin A, and Neurofilament.

    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Pancreas or brain
    Isotype:IgG2b /κ
    Immunogen:A synthetic peptide corresponding to aa416-433 of human NSE gamma
    Ordering Information
    Classification IVD
    Catalogue Number Z2351ML
    Classification IVD
    Catalogue Number Z2351ML
    Package Inserts
    IFU-NSE ZM24
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.