Preferred Clone

Formalin-fixed, paraffin-embedded human skeletal muscle stained with anti-myoglobin antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of skeletal muscle fibers.

Myoglobin

Soft Tissue Pathology

ZR69 Rabbit Monoclonal

Myoglobin is a cytosolic oxygen-binding protein responsible for the storage and diffusion of oxygen within myocytes. Expression of myoglobin is highest in skeletal and cardiac muscle. Myoglobin is well accepted as an O2-storage protein in muscle, capable of releasing O2 during periods of hypoxia or anoxia. In combination with other striated muscle markers such as vimentin and myogenin, myoglobin is helpful in the identification of rhabdomyosarcoma and tumors with skeletal muscle differentiation. Reportedly, myoglobin is expressed on epithelial cancer cells due to changed metabolic and environmental conditions.

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Skeletal muscle

Visualization:Cytoplasmic

Isotype:IgG

Immunogen:Recombinant human full-length Myoglobin (MB) protein

Ordering Information

USA International

Package Inserts

IFU-Myoglobin ZR69

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

Accept Reject

SDS