Human uterus stained with anti-desmin antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of smooth muscle cells.

Desmin

Soft Tissue Pathology

ZM34 Mouse Monoclonal

Desmin is an intermediate filament protein of both smooth and striated muscles. Antibody to desmin reacts with striated (skeletal and cardiac) as well as smooth muscle cells. In skeletal and cardiac muscles, the staining is confined to the Z-bands giving a characteristic striated appearance. Anti-desmin antibody is useful in identification of tumors of myogenic origin. It reacts with leiomyosarcomas (smooth muscle) as well as rhabdomyosarcomas (striated muscle).

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Skeletal muscle or rhabdomyosarcoma

Visualization:Cytoplasmic and luminal membrane

Isotype:IgG1 /κ

Immunogen:Recombinant human full-length desmin protein

Ordering Information

USA International

Package Inserts

IFU-Desmin ZM34

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

Accept Reject

SDS