Related Products

    Insulin

    Neuropathology/Endocrine
    ZM83 Mouse Monoclonal

    Antibodies recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Normal pancreas
    Visualization:Cytoplasmic
    Isotype:IgG1 /κ + IgG1 /κ
    Immunogen:Recombinant INS protein
    Ordering Information
    Classification IVD
    Catalogue Number Z2525ML
    Classification IVD
    Catalogue Number Z2525ML
    Package Inserts
    IFU-Insulin ZM83
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS