Inhibin-α

    Neuropathology/Endocrine
    ZM113 Mouse Monoclonal

    Zeta Inhibin-α Antibody.  Zeta’s recombinant mouse antibody recognizes Inhibin-α, a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH).  The Inhibin-α antibody binds a 47kDa protein, which is identified as alpha sub-unit of Inhibin.  Inhibin comprises two subunits, Inhibin A and Inhibin B. Each subunit consists of the same α subunit, covalently linked to 1 of 2 distinct subunits, β-α or β-β. Originally isolated from ovarian follicular fluid and characterized as a disulphide-linked dimeric glycoprotein, Inhibin-α belongs to the transforming growth factor β (TFGβ) superfamily. Antibodies against Inhibin-α are useful in making a differentiation between adrenal cortical tumors and renal cell carcinoma. Inhibin-α can also be used to identify the sex cord stromal tumors of the ovary as well as trophoblastic tumors also demonstrate cytoplasmic positivity.  The Inhibin-α antibody is also used to make the differential diagnosis of intra-uterine versus ectopic pregnancy in endometrial curetting.

    Zeta Corporation is a leader in recombinant monoclonal IVD antibodies for immunohistochemistry (IHC) offering 400+ tumor and tissue specific relevant products developed by a pathologist for pathologists.  Visit Precision Recombinant Antibodies – IVD Antibodies – About Zeta Corporation (zeta-corp.com) to learn more about Zeta Corporation.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Adrenal cortex, testis, corpus luteum
    Visualization:Cytoplasmic
    Isotype:IgG2a /κ
    Immunogen:A synthetic peptide (around aa 73-¬96) of α-subunit of human inhibin A protein
    Ordering Information
    Classification IVD
    Catalogue Number Z2413ML
    Classification IVD
    Catalogue Number Z2413ML
    Package Inserts
    IFU-Inhibin-α ZM113
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS