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    FoxP1

    Hematopathology
    ZR333 Rabbit Monoclonal

    Forkhead box protein P1 (FOXP1) is a transcriptional repressor. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B cell development. FOXP1 protein plays an important role in the specification and differentiation of lung epithelium, also acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program. FOXP1 is useful in subclassification of DLBCL and a high cutoff (≥80%) for FOXP1 is needed to achieve high specificity for the ABC subtype.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Tonsil
    Visualization:Nuclear
    Isotype:IgG
    Immunogen:Recombinant Human FOXP1 protein
    Ordering Information
    Classification IVD
    Catalogue Number Z2639RL
    Classification IVD
    Catalogue Number Z2639RL
    Package Inserts
    IFU-FoxP1 ZR333
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS