Cytokeratin, HMW

    Urinary Pathology
    34βE12 Mouse Monoclonal

    Cytokeratin 34bE12 antibody recognizes cytokeratin 1, 5, 10, and 14 in the Moll catalog (MW 68kDa, 58kDa, 56.5kDa, and 50kDa), respectively. Cytokeratin 34bE12 antibody promises to be a specific marker useful in differential identification of squamous carcinomas from adenocarcinomas and differential diagnosis of benign and malignant tumors of prostatic gland. In normal cells, it labels squamous, ductal and other complex epithelia. It reacts with benign small-acinar lesions of the prostate and does not react with hepatocytes, pancreatic acinar cells, proximal renal tubes or endometrial glands. In tumor cells, this antibody is reactive with both squamous and ductal neoplasms and variably with those derived from simple epithelium.

    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Squamous cell carcinoma, prostate
    Visualization:Membranous and cytoplasmic
    Isotype:IgG1 /κ
    Immunogen:Solubilized keratin extracted from human stratum corneum
    Ordering Information
    Classification IVD
    Catalogue Number Z2019ML
    Classification IVD
    Catalogue Number Z2019ML
    Package Inserts
    IFU-Cytokeratin, HMW 34βE12
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.