Human prostate tissue stained with anti-Keratin 5/6 antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of basal cells.

Cytokeratin 5/6

General & Epithelial Markers

D5/16B4 Mouse Monoclonal

Twenty human keratins are divided into acidic (pI <5.7) and basic (pI >6.0) subfamilies. Members of the acidic and basic subfamilies are found together in pairs. The composition of keratin pairs varies with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. Many studies have shown the usefulness of keratins as markers in cancer research and tumor identification.

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Mesothelioma, prostate

Visualization:Cytoplasmic

Isotype:IgG1 /κ

Immunogen:Isolated Cytokeratin 5

Ordering Information

USA International

Package Inserts

IFU-Cytokeratin 5/6 D5/16B4 - IVD

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

Accept Reject

SDS