Zeta Cytokeratin 14 Antibody. Zeta’s monoclonal mouse antibody recognizes Cytokeratin 14 (CK14), which belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). Cytokeratin 14 (CK14) is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. The Cytokeratin 14 (CK14) antibody is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. The Cytokeratin 14 (CK14) antibody is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. The Cytokeratin 14 (CK14) antibody is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, the Cytokeratin 14 (CK14) antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.
Zeta Corporation is a leader in recombinant monoclonal IVD antibodies for immunohistochemistry (IHC) offering 400+ tumor and tissue specific relevant products developed by a pathologist for pathologists. Visit Precision Recombinant Antibodies – IVD Antibodies – About Zeta Corporation (zeta-corp.com) to learn more about Zeta Corporation.