Preferred Clone

Human mantle cell lymphoma stained with anti-Cyclin D1 antibody using peroxidase-conjugate and DAB chromogen. Note the nuclear staining of lymphoma cells.

Cyclin D1

Hematopathology

ZR197 Rabbit Monoclonal

Cyclin D1 or PRAD-1 or bcl-1 is one of the key cell cycle regulators, and functions in association with cdk4 and / or cdk6 by phosphorylating the Rb protein. It is a putative proto-oncogene over expressed in a wide variety of human neoplasms including mantle cell lymphomas (MCL).

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Mantle cell lymphoma

Visualization:Nuclear

Isotype:IgG

Immunogen:A synthetic peptide from C-terminus of human cyclin D1

Ordering Information

USA International

Package Inserts

IFU-Cyclin D1 ZR197

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

Accept Reject

SDS