Zeta Chromogranin A Antibody. Zeta’s rabbit recombinant monoclonal antibody recognizes Chromogranin A, which is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. Chromogranin A is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of Chromogranin A and neuron specific enolase (NSE) (NSE Recombinant Antibody for IHC – Zeta Corporation (zeta-corp.com)) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining, and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of Chromogranin A and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express Chromogranin A.
Zeta Corporation is a leader in recombinant monoclonal IVD antibodies for immunohistochemistry (IHC) offering 400+ tumor and tissue specific relevant products developed by a pathologist for pathologists. Visit Precision Recombinant Antibodies – IVD Antibodies – About Zeta Corporation (zeta-corp.com) to learn more about Zeta Corporation.