123C3.D5 Mouse Monoclonal

    Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule which is glycosylated or sialylated to produce the mature species. NCAM (CD56) is reported to express on most neuroectodermal derived cell lines, tissues, and neoplasms such as retinoblastoma, medulloblastoma, astrocytoma, and neuroblastoma. It is also expressed on some mesodermally derived tumors such as rhabdomyosarcoma and also on natural killer cells.

    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Neuroblastoma, neuroendocrine carcinoma
    Visualization:Cell membrane
    Isotype:IgG1 /κ
    Immunogen:Membrane preparation of a small cell lung carcinoma
    Ordering Information
    Classification IVD
    Catalogue Number Z2038ML
    Classification IVD
    Catalogue Number Z2038ML
    Package Inserts
    IFU-CD56 123C3.D5
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.