CD21

    Hematopathology
    ZR419 Rabbit Monoclonal

    Zeta CD21 Antibody.  Zeta’s rabbit recombinant monoclonal antibody recognizes CD21, a protein of 140kDa which is identified as the complement receptor 2 (CR2/CD21).  CD21 is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFN alpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.

    Zeta Corporation is a leader in recombinant monoclonal IVD antibodies for immunohistochemistry (IHC) offering 400+ tumor and tissue specific relevant products developed by a pathologist for pathologists.  Visit Precision Recombinant Antibodies – IVD Antibodies – About Zeta Corporation (zeta-corp.com) to learn more about Zeta Corporation.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Tonsil, lymph node
    Visualization:Cell membrane
    Isotype:IgG
    Immunogen:Recombinant human CR2 (CD21) protein fragment (around aa 44-196)
    Ordering Information
    Classification IVD
    Catalogue Number Z2775RL
    Classification IVD (Non-EU)/ RUO (EU)
    Catalogue Number Z2775RL
    Package Inserts
    IFU-CD21 ZR419- IVD 0
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    IFU-CD21 ZR419 - RUO 0
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS