ZR417 Rabbit Monoclonal

    3-fucosyl-N-acetyllactosamine (3-FAL) or CD15 or X-hapten plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. CD15 is also expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin’s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.

    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Hodgkin lymphoma
    Visualization:Cell membrane and granular perinuclear
    Immunogen:Purified human neutrophils (FUT4/815); Myelomonocytic leukemia cells (BRA-4F1)
    Ordering Information
    Classification IVD
    Catalogue Number Z2773RL
    Classification IVD
    Catalogue Number Z2773RL
    Package Inserts
    IFU-CD15 ZR417
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.