Steroidogenic Factor-1 (SF-1)

    N1665 Mouse Monoclonal

    Steroidogenic Factor 1 (SF-1) is considered an orphan nuclear receptor that belongs to subfamily 5. It was found to be a regulator of steroidogenic enzyme gene expression. Oxysterols are suggested as its ligands. It is expressed in all steroidogenic tissues, including the adrenal cortex, testicular Sertoli cells, and Leydig cells, ovarian theca, hypothalamus, and anterior pituitary. SF-1 plays an important role in adrenal and gonadal development. SF-1 is highly valuable marker to determine the adrenocortical origin of an adrenal mass.

    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Adrenal cortical carcinoma
    Isotype:IgG1 /κ
    Immunogen:Synthesized peptide corresponding to amino acids 220-461 SF-1 protein
    Ordering Information
    Classification IVD
    Catalogue Number Z2223ML
    Classification IVD
    Catalogue Number Z2223ML
    Package Inserts
    IFU-Steroidogenic Factor-1 (SF-1) N1665
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.