p53

    General & Epithelial Markers
    DO-7 Mouse Monoclonal

    p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Colon carcinoma
    Visualization:Nuclear
    Isotype:IgG2b /κ
    Immunogen:Recombinant human wild type p53 protein expressed in E. coli
    Ordering Information
    Classification IVD
    Catalogue Number Z2029ML
    Classification IVD
    Catalogue Number Z2029ML
    Package Inserts
    IFU-p53 DO-7
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS