Zeta NGFR Antibody. Zeta’s recombinant mouse antibody recognizes NGFR (Nerve Growth Factor Receptor), the first of neurotrophin receptors to be isolated and is a member of the tumor necrosis factor (TNF) receptor family. NGFR has been shown to be a reliable marker for desmoplastic and neurotropic melanoma by several groups. Expression of NGFR is ubiquitous and not limited to the nervous system. NGFR is expressed in mature nonneural cells such as perivascular cells, follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells and myoepithelial cells. Studies in prostate and urothelial cancer suggest that NGFR may act as a tumor suppressor, negatively regulating cell growth and proliferation. The NGFR antibody labels the myoepithelial cells of breast ducts and intralobular fibroblasts of breast ducts and thus aides in the diagnosis of malignancy in the breast.
Zeta Corporation is a leader in recombinant monoclonal IVD antibodies for immunohistochemistry (IHC) offering 400+ tumor and tissue specific relevant products developed by a pathologist for pathologists. Visit Precision Recombinant Antibodies – IVD Antibodies – About Zeta Corporation (zeta-corp.com) to learn more about Zeta Corporation.