Zeta Neurofilament Antibody. Zeta’s recombinant rabbit antibody recognizes Neurofilament (NF-L), the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. The Neurofilament antibody reacts with a 68kDa protein, identified as a light subunit of neurofilaments. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M), and 200kDa (NF-H). The Neurofilament antibody stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively by the antibody to Neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express Neurofilament.
Zeta Corporation is a leader in recombinant monoclonal IVD antibodies for immunohistochemistry (IHC) offering 400+ tumor and tissue specific relevant products developed by a pathologist for pathologists. Visit Precision Recombinant Antibodies – IVD Antibodies – About Zeta Corporation (zeta-corp.com) to learn more about Zeta Corporation.