Myelin Basic Protein (MBP)

    Neuropathology/Endocrine
    ZR109 Monospecific Rabbit Monoclonal

    Zeta Myelin Basic Protein (MBP) Antibody.  Zeta’s recombinant rabbit antibody recognizes Myelin Basic Protein (MBP), the second most abundant protein in central nervous system (CNS) myelin, comprising 30% of the total protein and about 10% of the dry weight of myelin. Myelin Basic Protein (MBP) is the only structural protein found so far to be essential for formation of CNS myelin, and has been called the executive molecule of myelin. Myelin Basic Protein (MBP) can interact with a number of polyanionic proteins including actin, tubulin, calmodulin, and clathrin, and negatively charged lipids, and acquires structure on binding to them. Myelin Basic Protein (MBP) may act as a membrane actin-binding protein, which might allow it to participate in transmission of extracellular signals to the cytoskeleton in oligodendrocytes and tight junctions in myelin. Myelin Basic Protein (MBP) may be applicable as a marker for oligodendrogliomas.

    Zeta Corporation is a leader in recombinant monoclonal IVD antibodies for immunohistochemistry (IHC) offering 400+ tumor and tissue specific relevant products developed by a pathologist for pathologists.  Visit Precision Recombinant Antibodies – IVD Antibodies – About Zeta Corporation (zeta-corp.com) to learn more about Zeta Corporation.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Brain
    Visualization:Cytoplasmic
    Isotype:Rabbit IgG
    Immunogen:Recombinant fragment (around aa 150-250) of human MBP
    Ordering Information
    Classification IVD
    Catalogue Number Z2411RL
    Classification IVD
    Catalogue Number Z2411RL
    Package Inserts
    IFU-Myelin Basic Protein (MBP) ZR109
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS