Mesothelin

    Lung/Mediastinum Pathology
    ZM25 Monospecific Mouse Monoclonal

    Zeta’s mouse monoclonal antibody recognizes Mesothelin, a 40kDa glycosyl-phosphatidylinositol-anchored glycoprotein cleaved from a 69kDa precursor protein. Mesothelin immunoreactivity is high in cancers of the ovary (serous papillary, endometrioid and undifferentiated) and pancreas, with less frequent staining seen in adenocarcinomas of the endometrium, lung and stomach/esophagus. Mesothelin is one of the most sensitive markers for mesothelioma.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Mesothelioma
    Visualization:Cytoplasmic
    Isotype:IgG2b /κ
    Immunogen:Recombinant human mesothelin (MSLN) protein fragment (around aa 273-407)
    Ordering Information
    Classification IVD
    Catalogue Number Z2353ML
    Classification IVD
    Catalogue Number Z2353ML
    Package Inserts
    IFU-Mesothelin ZM25 - IVDL
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS