Breast Pathology
    ZM67 Mouse Monoclonal

    Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in breast and neuroendocrine tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including neuroendocrine tumor and breast carcinoma. In general, Ki-67 is a good marker of proliferating cell populations.

    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Spleen, tonsil, or breast carcinomas
    Immunogen:Recombinant human Ki67 protein fragment (around aa2293-2478)
    Ordering Information
    Classification IVD
    Catalogue Number Z2377ML
    Classification IVD
    Catalogue Number Z2377ML
    Package Inserts
    IFU-Ki-67 ZM67
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.