Human colon carcinoma stained with anti-keratin 20 antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of carcinoma glands.

Cytokeratin 20

GI Pathology

ZR429 Rabbit Monoclonal

Zeta’s rabbit recombinant monoclonal antibody recognizes an intermediate filament protein of 46kDa, identified as Cytokeratin 20 (CK20). Cytokeratin 20 (CK20) is abundantly expressed in goblet cells and enterocytes of the gastrointestinal tract. Cytokeratin 20 (CK20) is a useful marker of pancreatic and colorectal cancer. Cytokeratin 20 (CK20) is expressed under normal, hyperplastic and neoplastic conditions. Cytokeratin 20 has been detected in adenocarcinomas of the colon, stomach and biliary tract whereas breast carcinomas are generally non-reactive.

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Colon carcinoma

Visualization:Cytoplasmic

Isotype:IgG

Immunogen:Recombinant human KRT20 protein fragment (around aa 196-323)

Ordering Information

USA International

Package Inserts

IFU-Cytokeratin 20 ZR429 - IVD 0

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

Accept Reject

IFU-Cytokeratin 20 ZR429 - RUO -0

Regulatory Notice

Accept Reject

SDS