Anti-Cytokeratin (CAM 5.2) reagent primarily reacts with human keratin proteins that correspond to Moll`s peptides #7 and #8, MW 48 and 52 kDa, respectively. ZM144 is a mixture of equal CK7 (OV-TL 12/30) and CK8 (ZM123). Cytokeratin 7 and 8 are present on secretory epithelia of normal human tissue but not on the stratified squamous epithelium. Anti-Cytokeratin (ZM144) stains most epithelial-derived tissue, including liver, renal tubular epithelium, and hepatocellular and renal cell carcinomas. Anti-Cytokeratin (ZM144) may not react with some squamous cell carcinomas.