Formalin-fixed, paraffin-embedded human liver stained with antibody ZM144 using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of hepatocytes (weak) and bile ducts (strong).

Cytokeratin (Like CAM5.2)

General & Epithelial Markers

ZM144 Mouse Monoclonal

Anti-Cytokeratin (CAM 5.2) reagent primarily reacts with human keratin proteins that correspond to Moll`s peptides #7 and #8, MW 48 and 52 kDa, respectively. ZM144 is a mixture of equal CK7 (OV-TL 12/30) and CK8 (ZM123). Cytokeratin 7 and 8 are present on secretory epithelia of normal human tissue but not on the stratified squamous epithelium. Anti-Cytokeratin (ZM144) stains most epithelial-derived tissue, including liver, renal tubular epithelium, and hepatocellular and renal cell carcinomas. Anti-Cytokeratin (ZM144) may not react with some squamous cell carcinomas.

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Ovarian carcinoma

Visualization:Cytoplasmic

Isotype:IgG1 /κ+IgG1 /κ

Immunogen:OTN II ovarian carcinoma cell line / Recombinant full-length human KRT8 protein

Ordering Information

USA International

Package Inserts

IFU-Cytokeratin ZM144

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

Accept Reject

SDS