preferred clone

Formalin-fixed, paraffin-embedded bone marrow stained with anti-CD71 antibody using peroxidase-conjugated and DAB chromogen. Note the cytoplasmic staining of erythroid precursors

CD71

Hematopathology

ZM136 Mouse Monoclonal

It recognizes a ~90-95kDa protein identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa (Workshop IV). This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and helpful in predicting clinical behavior or response to therapy in several malignancies, including breast cancer.

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Bone marrow

Visualization:Cytoplasmic

Isotype:IgG1 /κ

Immunogen:Recombinant fragment of human TFRC receptor

Ordering Information

USA International

Package Inserts

IFU-CD71 ZM136

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

Accept Reject

SDS