Human diffuse large B cell lymphoma stained with anti-CD45/RB (LCA) antibody using peroxidase-conjugate and DAB chromogen. Note cell membrane staining of lymphoma cells.

CD45RB (LCA)

Hematopathology

2B11+PD7/26 Mouse Monoclonal

CD45 leukocyte common antigen (LCA) belongs to the family of at least four isoforms of membrane glycoproteins (220, 205, 190, 180kDa) expressed on hematopoietic cell lines but absent on non-hematopoietic cell lines, normal and malignant non-hematopoietic tissues. The intracellular portion of these molecules have protein phosphatase activity and are involved in regulation of transmembrane signals. Antibody to CD45 is useful in differential identification of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Tonsil or lymph node

Visualization:Cell membrane

Isotype:IgG1 /κ + IgG1 /κ

Immunogen:PD7/26/16: human peripheral blood lymphocytes maintained in T cell growth factor; 2B11: isolated neoplastic cells from T cell lymphoma

Ordering Information

USA International

Package Inserts

IFU-CD45RB (LCA) 2B11+PD7/26

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

Accept Reject

SDS