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    CD45RB (LCA)

    2B11+PD7/26 Mouse Monoclonal

    CD45 leukocyte common antigen (LCA) belongs to the family of at least four isoforms of membrane glycoproteins (220, 205, 190, 180kDa) expressed on hematopoietic cell lines but absent on non-hematopoietic cell lines, normal and malignant non-hematopoietic tissues. The intracellular portion of these molecules have protein phosphatase activity and are involved in regulation of transmembrane signals. Antibody to CD45 is useful in differential identification of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.

    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Tonsil or lymph node
    Visualization:Cell membrane
    Isotype:IgG1 /κ + IgG1 /κ
    Immunogen:PD7/26/16: human peripheral blood lymphocytes maintained in T cell growth factor; 2B11: isolated neoplastic cells from T cell lymphoma
    Ordering Information
    Classification IVD
    Catalogue Number Z2093ML
    Classification IVD
    Catalogue Number Z2093ML
    Package Inserts
    IFU-CD45RB (LCA) 2B11+PD7/26
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.