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    ZR402 Rabbit Monoclonal

    Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFkappa B and SAPK/JNK and induces apoptosis.

    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Visualization:Cell surface
    Immunogen:Recombinant human CD27 protein fragment (aa 28-170)
    Ordering Information
    Classification IVD
    Catalogue Number Z2758RL
    Classification IVD
    Catalogue Number Z2758RL
    Package Inserts
    IFU-CD27 ZR402
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.