Calponin-1

    Soft Tissue Pathology
    ZR297 Rabbit Monoclonal

    Zeta Calponin-1 Antibody.  Zeta’s rabbit recombinant antibody recognizes Calponin-1.  Multiple isoelectric variants of Calponin have been identified, however only two molecular weight isoforms exist; a 34kDa form and a 29kDa form. Expression of the 29kDa form, I-Calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, Zeta’s recombinant antibody to Caplonin-1 reacts with only the 34kDa form of Calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin-1 is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin-1 expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.

    Zeta Corporation is a leader in recombinant monoclonal IVD antibodies for immunohistochemistry (IHC) offering 400+ tumor and tissue specific relevant products developed by a pathologist for pathologists.  Visit Precision Recombinant Antibodies – IVD Antibodies – About Zeta Corporation (zeta-corp.com) to learn more about Zeta Corporation.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Normal breast tissue
    Visualization:Cytoplasmic
    Isotype:IgG
    Immunogen:Recombinant human full-length CNN1 protein
    Ordering Information
    Classification IVD
    Catalogue Number Z2612RL
    Classification IVD
    Catalogue Number Z2612RL
    Package Inserts
    IFU-Calponin-1 ZR297
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS