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    Thyroid Stimulating Hormone

    Neuropathology/Endocrine
    ZM294 Mouse Monoclonal

    Zeta Thyroid Stimulating Hormone (TSH) Antibody.  Zeta’s recombinant mouse antibody recognizes Thyroid Stimulating Hormone (TSH), a protein synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland.

    The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and Thyroid Stimulating Hormone (TSH) are dimers consisting of alpha and beta subunits that are associated non-covalently. The alpha subunits of these hormones are identical; however, their beta chains are unique and confer biological specificity.

    Thyroid Stimulating Hormone (TSH) is synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. Thyroid Stimulating Hormone (TSH) stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3).  Thyroid Stimulating Hormone (TSH) production is controlled by a Thyrotropin-Releasing Hormone (TRH), which is manufactured in the hypothalamus and transported to the pituitary gland, where it increases Thyroid Stimulating Hormone (TSH) production and release. Somatostatin is also produced by the hypothalamus and has an opposite effect on the pituitary production of Thyroid Stimulating Hormone (TSH), decreasing or inhibiting its release. Thyroid Stimulating Hormone (TSH) is a useful marker in classification of pituitary tumors and the study of pituitary disease.

    Zeta Corporation is a leader in recombinant monoclonal IVD antibodies for immunohistochemistry (IHC) offering 400+ tumor and tissue specific relevant products developed by a pathologist for pathologists.  Visit Precision Recombinant Antibodies – IVD Antibodies – About Zeta Corporation (zeta-corp.com) to learn more about Zeta Corporation.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Pituitary
    Visualization:Cytoplasmic
    Isotype:IgG1/κ
    Immunogen:Recombinant human TSH beta fragment
    Ordering Information
    Classification IVD
    Catalogue Number Z2608ML
    Classification IVD
    Catalogue Number Z2608ML
    Package Inserts
    IFU-Thyroid Stimulating Hormone ZM294 - IVDL
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS