Related Products

    Napsin-A

    Lung/Mediastinum Pathology
    ZM11 Monospecific Mouse Monoclonal

    Zeta Napsin-A Antibody.  Zeta’s recombinant mouse antibody recognizes Napsin-A.  Napsin-A is a pepsin-like aspartic proteinase connected with the maturation of surfactant protein B. There are two closely related Napsins, Napsin A and Napsin B. Napsin-A is expressed as a single-chain protein. Immunohistochemical studies revealed high expression levels of Napsin-A in the human lung and kidney but low expression in the spleen. Napsin A is expressed in type II pneumocytes and adenocarcinomas of the lung. The high specificity expression of Napsin-A in adenocarcinomas of the lung is helpful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.

    Zeta Corporation is a leader in recombinant monoclonal IVD antibodies for immunohistochemistry (IHC) offering 400+ tumor and tissue specific relevant products developed by a pathologist for pathologists.  Visit Precision Recombinant Antibodies – IVD Antibodies – About Zeta Corporation (zeta-corp.com) to learn more about Zeta Corporation.

    Napsin is a pepsin-like aspartic proteinase, in the A1 clan of the AA clade of proteinases. There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein with the molecular weight of approximately 38 kDa. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Lung adenocarcinoma
    Visualization:Cytoplasmic
    Isotype:IgG1 /κ
    Immunogen:Recombinant fragment of human napsin protein
    Ordering Information
    Classification IVD
    Catalogue Number Z2294ML
    Classification IVD
    Catalogue Number Z2294ML
    Package Inserts
    IFU-Napsin-A ZM11
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS