Human basal cell carcinoma stained with anti-keratin 8 antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of tumor cells.

Cytokeratin 8

General & Epithelial Markers

ZM123 Mouse Monoclonal

Keratin 8 belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with keratin 18. Keratin 8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin polypeptides 8 and 18.

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Breast carcinoma

Visualization:Cytoplasmic

Isotype:IgG1 /κ

Immunogen:Recombinant full-length human KRT8 protein

Ordering Information

USA International

Package Inserts

IFU-Cytokeratin 8 ZM123 - IVDL

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

Accept Reject

SDS