Human liver stained with anti-keratin 8/18 antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of ductal cells (strong) and hepatocytes (weak).

Cytokeratin 8/18

General & Epithelial Markers

B22.1 & B23.1 Mouse Monoclonal

Clone 5D3 antibody recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. Clone K8.8 + DC10 is indistinguishable from the staining obtained with monoclonal antibody 5D3.

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Skin, breast carcinoma

Visualization:Cytoplasmic

Isotype:IgG1 /κ + IgG1 /κ

Immunogen:Cytokeratins purified from breast cancer MCF-7 cells

Ordering Information

USA International

Package Inserts

IFU-Cytokeratin 8/18 B22.1 & B23.1

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

Accept Reject

SDS