Preferred Clone

Human colon carcinoma stained with anti-keratin 20 antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of carcinoma glands.

Cytokeratin 20

GI Pathology

ZM42 Monospecific Mouse Monoclonal

This MAb recognizes an intermediate filament protein of 46kDa, identified as cytokeratin 20 (CK20). CK20 is abundantly expressed in goblet cells and enterocytes of the gastrointestinal tract. It is a useful marker of pancreatic and colorectal cancer. CK20 is expressed under normal, hyperplastic and neoplastic conditions. It has been detected in adenocarcinomas of the colon, stomach and biliary tract. Breast carcinomas are generally non-reactive.

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Colon carcinoma

Visualization:Cytoplasmic

Isotype:IgG2b /κ

Immunogen:Recombinant human KRT20 protein fragment (around aa 196-323)

Ordering Information

USA International

Package Inserts

IFU-Cytokeratin 20 ZM42

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

Accept Reject

SDS