Human pancreatic ducts stained with anti-keratin 19 antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of ductal cells.

Cytokeratin 19

Neuropathology/Endocrine

BA17 Mouse Monoclonal

Cytokeratin 19 is a member of type I acidic subfamily of intermediate filaments. It is expressed in various different human tissues except in liver. Keratin 19 is not expressed in hepatocytes, therefore, antibody to CK19 is useful in the identification of liver metastasis.BA17reacts with the MCF-7 cells, which are known to contain CK19. It shows no reaction with the cells lacking CK19 such as A431 and Hela. In combination with HBME1, CK19 is useful in differentiating thyroid carcinoma from benign thyroid follicles.

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Skin

Visualization:Cytoplasmic

Isotype:IgG1 /κ

Immunogen:Detergent-insoluble extract of human mammary epithelial organoids

Ordering Information

USA International

Package Inserts

IFU-Cytokeratin 19 BA17 - IVD

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

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SDS