CD45RA

    Hematopathology
    ZR118 Rabbit Monoclonal

     Zeta CD45RA Antibody.  Zeta’s recombinant rabbit antibody recognizes CD45RA, is exclusively expressed in haematolymphoid cells.  CD45RA is a member of the CD45 family of single-chain transmembrane glycoproteins, consisting of at least four isoforms that share a common large intracellular domain. CD45 family members’ cellular domains are rod-shaped and heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1q31-32. CD45RA is exclusively expressed in haematolymphoid cells. Almost all haematolymphoid cells, including precursor cells and mature B- and T-lymphocytes, granulocytes, monocytes/histiocytes and interdigitating reticulum cells and follicular dendritic cells, express CD45RA. CD45RA protein is detected in most haematolymphoid neoplasms, such as leukemias and malignant lymphomas. Overall, about 90% of malignant lymphomas are CD45RA positive. CD45RA is an essential marker in the primary tumor screening panel to identify haematolymphoid differentiation. Loss of CD45RA in precursor B-cell neoplasms is a negative prognostic parameter.

    Zeta Corporation is a leader in recombinant monoclonal IVD antibodies for immunohistochemistry (IHC) offering 400+ tumor and tissue specific relevant products developed by a pathologist for pathologists.  Visit Precision Recombinant Antibodies – IVD Antibodies – About Zeta Corporation (zeta-corp.com) to learn more about Zeta Corporation.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Lymph node or tonsil
    Visualization:Cell membrane
    Isotype:IgG
    Immunogen:Recombinant full-length human PTPRC protein
    Ordering Information
    Classification IVD
    Catalogue Number Z2681RL
    Classification IVD
    Catalogue Number Z2681RL
    Package Inserts
    IFU-CD45RA ZR118
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS