Related Products

    CD33

    Hematopathology
    PWS44 Monospecific Mouse Monoclonal

    Zeta CD33 Antibody.  Zeta Corporation’s mouse monoclonal antibody recognizes CD33 (gp67, or siglec-3), a 67 kDa glycosylated transmembrane protein that is a member of the sialic acid-binding immunoglobulin-like lectin (siglec) family. CD33 plays a role in cell-cell interactions, signaling, and modulation of immune cell function. The CD33 antibody may be particularly advantageous for cases of acute myeloid leukemia, minimally differentiated (AML-M0) and acute monocytic leukemia (AML-M5), in which other paraffin section markers of myeloid differentiation (such as anti-myeloperoxidase) may be negative. All cases of myeloid sarcoma in this study showed anti-CD33 positivity in the myeloid and monocytic subsets, allowing for easy interpretation. The excellent sensitivity and specificity for myelomonocytic lineage makes this antibody to CD33 a useful diagnostic marker for myeloid sarcoma. In addition, Zeta’s CD33 antibody may be useful in determining CD33 expression on paraffin-embedded material if flow cytometry studies were not initially performed for patients with acute leukemia. Analysis of CD33 expression in paraffin-embedded bone marrow biopsy specimens provides another alternative when evaluating acute leukemias.

    Zeta Corporation is a leader in recombinant monoclonal IVD antibodies for immunohistochemistry (IHC) offering 400+ tumor and tissue specific relevant products developed by a pathologist for pathologists.  Visit Precision Recombinant Antibodies – IVD Antibodies – About Zeta Corporation (zeta-corp.com) to learn more about Zeta Corporation.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Spleen
    Visualization:Cytoplasmic
    Isotype:IgG2b
    Immunogen:Prokaryotic recombinant protein corresponding to a region of the C2 domain of the human CD33 molecule
    Ordering Information
    Classification IVD
    Catalogue Number Z2322ML
    Classification IVD (Non-EU)/ RUO (EU)
    Catalogue Number Z2322ML
    Package Inserts
    IFU-CD33 PWS44 - IVD
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    IFU-CD33 PWS44 - RUO
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS