Caldesmon

    Soft Tissue Pathology
    ZR413 Rabbit Monoclonal

    Zeta Caldesmon Antibody.  Zeta’s recombinant antibody recognizes Caldesmon, a protein of 150kDa, which is identified as the high molecular weight variant.  The Zeta recombinant antibody specifically recognizes h-caldesmon that is predominantly expressed in smooth muscle.  The Cadesmon antibody does not recognize l-caldesmon, the second variant of Caldesmon, which is found in non-muscle tissue and cells.  Neither of the variants are detected in skeletal muscle.  The Zeta antibody recognizes h-caldesmon in Western blots of human oartic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction which interacts with actin, myosin, tryopomyosin and calmodulin. Zeta’s Caldesmon antibody detects smooth muscle and tumors of smooth muscle, myofibroblastic and myoepithelial differentiation. Zeta’s Caldesmon antibody is also useful in the differentiation of epithelioid mesothelioma from serous papillary carcinoma of the ovary.

    Zeta Corporation is a leader in recombinant monoclonal IVD antibodies for immunohistochemistry (IHC) offering 400+ tumor and tissue specific relevant products developed by a pathologist for pathologists.  Visit Precision Recombinant Antibodies – IVD Antibodies – About Zeta Corporation (zeta-corp.com) to learn more about Zeta Corporation.

     

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Uterus, colon carcinoma
    Visualization:Cytoplasmic
    Isotype:IgG
    Immunogen:Recombinant full-length human CALD1 protein
    Ordering Information
    Classification IVD
    Catalogue Number Z2769RL
    Classification IVD (Non-EU)/ RUO (EU)
    Catalogue Number Z2769RL
    Package Inserts
    IFU-Caldesmon ZR413 - IVD 0
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    IFU-Caldesmon ZR413 RUO 0
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS