Preferred Clone
Normal human renal tissue stained with anti-CA IX antibody using peroxidase-conjugate and DAB chromogen. Note the membranous staining of tubular cells.
Recognizes a glycoprotein of ~200kDa, identified as carbonic anhydrase IX (CAIX/gp200). In the normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule and focally along the luminal surface of Bowman’s capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may help investigate carcinomas of proximal nephrogenic differentiation, especially those showing tubular differentiation.
Specifications
Species Reactivity:Humans; others not tested
Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Supplied As:Buffer with protein carrier and preservative
Storage:Store at 2ºC to 8ºC
Control:Normal renal tissue
Visualization:Membrane
Isotype:IgG
Immunogen:Recombinant human CA9 protein fragment (around aa 314-410) (exact sequence is proprietary)
Ordering Information
Package Inserts
SDS