C4d

    Transplantation Pathology
    ZM78 Mouse Monoclonal

    Zeta C4d Antibody.  Zeta’s mouse recombinant antibody recognizes C4d, a stable split product remnant of classical complement activation, which becomes covalently bound to endothelium and basement membrane, after induction of the classical antibody-induced pathway. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, C4d component can be detected in peritubular capillaries in both chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. C4d has been shown to be a significant predictor of transplant kidney graft survival and is an aid in treating acute rejection

    Zeta Corporation is a leader in recombinant monoclonal IVD antibodies for immunohistochemistry (IHC) offering 400+ tumor and tissue specific relevant products developed by a pathologist for pathologists.  Visit Precision Recombinant Antibodies – IVD Antibodies – About Zeta Corporation (zeta-corp.com) to learn more about Zeta Corporation.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Acute rejected kidney transplant
    Visualization:Membrane or cytoplasmic
    Isotype:IgG1 /κ
    Immunogen:Recombinant full-length human complement 4d protein
    Ordering Information
    Classification IVD
    Catalogue Number Z2388ML
    Classification IVD
    Catalogue Number Z2388ML
    Package Inserts
    IFU-C4d ZM78 - IVDL
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS