Lung/Mediastinum Pathology
    8G7G3/1 Mouse Monoclonal

    TTF-1(Thyroid transcription factor-1) is a member of the NKX2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. TTF-1 is detected in primary lung adenocarcinomas and small cell carcinomas and is absent in colon and breast carcinomas. Staining with TTF-1 antibody is useful for distinguishing between tumors of lung and non-lung origin.

    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Normal thyroid or lung
    Isotype:IgG1 /κ
    Immunogen:Rat TTF-1 recombinant protein
    Ordering Information
    Classification IVD
    Catalogue Number Z2069ML
    Classification IVD
    Catalogue Number Z2069ML
    Package Inserts
    IFU-TTF-1 8G7G3/1 - IVD
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.