ZR284 Rabbit Monoclonal

    The T cell intracellular antigen 1 (TIA-1) is a 17-kDa cytoplasmic granule associated protein also designated as GMP-17, for granule membrane protein of 17 kDa. The GMP-17/TIA-1 molecule is expressed in cells possessing cytolytic potential and could be involved in the signaling cascade of Fas (CD95)-mediated apoptosis. Within hematopoietic cell lines, the 2G9 monoclonal antibody (mAb) reacts with about 90% of CD16+, 50 – 60% of CD8+, and less than 10% of CD4+ normal peripheral blood lymphocytes. It reacts with almost all monocytes and granulocytes. This antibody also reacts with CD4+ activated T-cell clones, activated NK cell clones, and Con activated thymocytes, but not with B lymphocytes or B-cell lines.

    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Immunogen:Full-length of human TIA-1 protein
    Ordering Information
    Classification IVD
    Catalogue Number Z2599RL
    Classification IVD
    Catalogue Number Z2599RL
    Package Inserts
    IFU-TIA-1 ZR284
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.